458 research outputs found

    Design and operation of a prototype interaction point beam collision feedback system for the International Linear Collider

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    A high-resolution, intratrain position feedback system has been developed to achieve and maintain collisions at the proposed future electron-positron International Linear Collider (ILC). A prototype has been commissioned and tested with a beam in the extraction line of the Accelerator Test Facility at the High Energy Accelerator Research Organization in Japan. It consists of a stripline beam position monitor (BPM) with analogue signal-processing electronics, a custom digital board to perform the feedback calculation, and a stripline kicker driven by a high-current amplifier. The closed-loop feedback latency is 148 ns. For a three-bunch train with 154 ns bunch spacing, the feedback system has been used to stabilize the third bunch to 450 nm. The kicker response is linear, and the feedback performance is maintained, over a correction range of over ±\pm60 {\mu}m. The propagation of the correction has been confirmed by using an independent stripline BPM located downstream of the feedback system. The system has been demonstrated to meet the BPM resolution, beam kick, and latency requirements for the ILC

    Molecular epidemiology of human rhinovirus infections in Kilifi, coastal Kenya

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    This study reports pediatric surveillance over 3 years for human rhinovirus (HRV) at the District Hospital of Kilifi, coastal Kenya. Nasopharyngeal samples were collected from children presenting at outpatient clinic with no signs of acute respiratory infection, or with signs of upper respiratory tract infection, and from children admitted to the hospital with lower respiratory tract infection. Samples were screened by real-time reverse transcriptase polymerase chain reaction (real-time RT-PCR) and classified further to species by nucleotide sequencing of the VP4/VP2 junction. Of 441 HRV positives by real-time RT-PCR, 332 were classified to species, with 47% (155) being HRV-A, 5% (18) HRV-B, and 48% (159) HRV-C. There was no clear seasonal pattern of occurrence for any species. The species were present in similar proportions in the inpatient and outpatient sample sets, and no significant association between species distribution and the severity of lower respiratory tract infection in the inpatients could be determined. HRV sequence analysis revealed multiple but separate clusters in circulation particularly for HRV-A and HRV-C. Most HRV-C clusters were distinct from reference sequences downloaded from GenBank. In contrast, most HRV-A and HRV-B sequences clustered with either known serotypes or strains from elsewhere within Africa and other regions of the world. This first molecular epidemiological study of HRV in the region defines species distribution in accord with reports from elsewhere in the world, shows considerable strain diversity and does not identify an association between any species and disease severity

    Future disease risk and vulnerability maps

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    Genetic mapping of legume orthologs reveals high conservation of synteny between lentil species and the sequenced genomes of Medicago and chickpea.

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    Lentil (Lens culinaris Medik.) is a global food crop with increasing importance for food security in south Asia and other regions. Lens ervoides, a wild relative of cultivated lentil, is an important source of agronomic trait variation. Lens is a member of the galegoid clade of the Papilionoideae family, which includes other important dietary legumes such as chickpea (Cicer arietinum) and pea (Pisum sativum), and the sequenced model legume Medicago truncatula. Understanding the genetic structure of Lens spp. in relation to more fully sequenced legumes would allow leveraging of genomic resources. A set of 1107 TOG-based amplicons were identified in L. ervoides and a subset thereof used to design SNP markers for mapping. A map of L. ervoides consisting of 377 SNP markers spread across seven linkage groups was developed using a GoldenGate genotyping array and single SNP marker assays. Comparison with maps of M. truncatula and L. culinaris documented considerable shared synteny and led to the identification of a few major translocations and a major inversion that distinguish Lens from M. truncatula, as well as a translocation that distinguishes L. culinaris from L. ervoides. The identification of chromosome-level differences among Lens spp. will aid in the understanding of introgression of genes from L. ervoides into cultivated L. culinaris, furthering genetic research and breeding applications in lentil

    Caught between Energy Demands and Food Needs: Dilemmas of Smallholder Farmers in Njoro, Kenya

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    Smallholders in rural Kenya, like their counterparts in tropical Africa currently face acute shortage of fuel wood for domestic use. There has been rapid population increase in the last few decades resulting in increased demand for food crops. This has led to the expansion of area under subsistence agriculture eating into indigenous forests, the traditional source of wood fuel. This situation has been compounded by the limited access to alternative sources of domestic energy in rural parts of Kenya. The recent upsurge in the cost of fossil-derived fuels as well as in hydro-generated electricity has left the smallholder farmer with wood as the sole source of fuel. This paper therefore examines the conflicting demands of domestic fuel needs and foods. Key research questions were: What are the household domestic energy demand and constraints? What is the household food demand and constraint among smallholders? How do the smallholders reconcile these competing basic needs? The paper reflects on the constraints of smallholders in their quest to fulfill their food and energy needs. The discussed model is a result based on discussions between the researchers and focus group discussions drawn from smallholder farmers. The primary data gathered from the discussions is augmented by secondary data to draw imperative implications on domestic energy use and food needs. The results indicate an average annual per capita wood fuel demand of 1.99 m3 and a deficit of 8.816 m3 per household. The deficit is usually catered for through purchase of wood fuel from the market, which has an implication on the pressure exerted on the forestry resources. This paper shows that households in Njoro have turned to desperate coping mechanisms and strategies such as use of maize straw, pruning and fallen twigs. The results of this study provide insights on how the dilemma may be resolved in a smallholder setup and suggest local policy options

    A sub-micron resolution, bunch-by-bunch beam trajectory feedback system and its application to reducing wakefield effects in single-pass beamlines

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    A high-precision intra-bunch-train beam orbit feedback correction system has been developed and tested in the ATF2 beamline of the Accelerator Test Facility at the High Energy Accelerator Research Organization in Japan. The system uses the vertical position of the bunch measured at two beam position monitors (BPMs) to calculate a pair of kicks which are applied to the next bunch using two upstream kickers, thereby correcting both the vertical position and trajectory angle. Using trains of two electron bunches separated in time by 187.6~ns, the system was optimised so as to stabilize the beam offset at the feedback BPMs to better than 350~nm, yielding a local trajectory angle correction to within 250~nrad. The quality of the correction was verified using three downstream witness BPMs and the results were found to be in agreement with the predictions of a linear lattice model used to propagate the beam trajectory from the feedback region. This same model predicts a corrected beam jitter of c.~1~nm at the focal point of the accelerator. Measurements with a beam size monitor at this location demonstrate that reducing the trajectory jitter of the beam by a factor of 4 also reduces the increase in the measured beam size as a function of beam charge by a factor of c.~1.6.Comment: 16 pages, 10 figure

    Photoreflectance analysis of a GaInP/GaInAs/Ge multijunction solar cell

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    We have analyzed the photoreflectance spectra of a GaInP/GaInAs/Ge triple junction solar cell. The spectra reveal signatures from the window layer and middle and top subcells included in the stack. Additional contributions from the multilayer buffer introduced between the mismatched bottom and middle cells have been detected. Franz–Keldysh oscillations (FKOs) dominate the spectra above the fundamental bandgaps of the GaInP and GaInAs absorbers. From the FKO analysis, we have estimated the dominant electric fields within each subcell. In light of these results, photoreflectance is proposed as a useful diagnostic tool for quality assessment of multijunction structures prior to completion of the device or at earlier stages during its processing

    Performance analysis of AlGaAs/GaAs tunnel junctions for ultra-high concentration photovoltaics

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    An n(++)-GaAs/p(++)-AlGaAs tunnel junction with a peak current density of 10 100Acm(-2) is developed. This device is a tunnel junction for multijunction solar cells, grown lattice-matched on standard GaAs or Ge substrates, with the highest peak current density ever reported. The voltage drop for a current density equivalent to the operation of the multijunction solar cell up to 10 000 suns is below 5 mV. Trap-assisted tunnelling is proposed to be behind this performance, which cannot be justified by simple band-to-band tunnelling. The metal-organic vapour-phase epitaxy growth conditions, which are in the limits of the transport-limited regime, and the heavy tellurium doping levels are the proposed origins of the defects enabling trap-assisted tunnelling. The hypothesis of trap-assisted tunnelling is supported by the observed annealing behaviour of the tunnel junctions, which cannot be explained in terms of dopant diffusion or passivation. For the integration of these tunnel junctions into a triple-junction solar cell, AlGaAs barrier layers are introduced to suppress the formation of parasitic junctions, but this is found to significantly degrade the performance of the tunnel junctions. However, the annealed tunnel junctions with barrier layers still exhibit a peak current density higher than 2500Acm(-2) and a voltage drop at 10 000 suns of around 20 mV, which are excellent properties for tunnel junctions and mean they can serve as low-loss interconnections in multijunction solar cells working at ultra-high concentrations

    A Counterpart to the Radial Orbit Instability in Triaxial Stellar Systems

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    Self-consistent solutions for triaxial mass models are highly non-unique. In general, some of these solutions might be dynamically unstable, making them inappropriate as descriptions of steady-state galaxies. Here we demonstrate for the first time the existence in triaxial galaxy models of an instability similar to the radial-orbit instability of spherical models. The instability manifests itself when the number of box orbits, with predominantly radially motions, is sufficiently large. N-body simulations verify that the evolution is due neither to chaotic orbits nor to departures of the model from self-consistency, but rather to a collective mode. The instability transforms the triaxial model into a more prolate, but still triaxial, configuration. Stable triaxial models are obtained when the mass contribution of radial orbits is reduced. The implications of our results for the shapes of dark-matter halos are discussed.Comment: 14 pages, 16 figure
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